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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPL5
All Species:
39.7
Human Site:
S272
Identified Species:
58.22
UniProt:
P46777
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46777
NP_000960.2
297
34363
S272
R
W
N
R
P
K
M
S
L
A
Q
K
K
D
R
Chimpanzee
Pan troglodytes
XP_513564
406
45547
S381
R
W
N
R
P
K
M
S
L
A
Q
K
K
D
R
Rhesus Macaque
Macaca mulatta
XP_001092402
249
28816
D225
I
M
G
Q
N
V
A
D
Y
M
R
Y
L
M
E
Dog
Lupus familis
XP_537074
247
28053
L223
W
N
R
P
K
M
S
L
A
Q
K
K
D
R
V
Cat
Felis silvestris
Mouse
Mus musculus
P47962
297
34382
S272
R
W
N
R
P
K
M
S
L
A
Q
K
K
D
R
Rat
Rattus norvegicus
P09895
297
34440
S272
R
W
N
R
P
K
M
S
L
A
Q
K
K
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515074
357
40536
S332
R
W
N
R
P
K
M
S
L
A
Q
K
K
D
R
Chicken
Gallus gallus
P22451
297
34073
S272
R
V
N
S
T
K
M
S
L
A
Q
K
K
D
R
Frog
Xenopus laevis
P15125
296
34087
S272
R
W
N
R
A
K
L
S
L
E
Q
K
K
D
R
Zebra Danio
Brachydanio rerio
NP_956050
297
34066
T272
R
W
N
R
A
K
L
T
L
A
Q
R
K
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W5R8
299
34018
T274
R
W
N
A
K
K
L
T
N
E
Q
R
K
T
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49405
293
33368
L269
K
R
H
T
A
K
R
L
T
Y
D
E
R
K
Q
Sea Urchin
Strong. purpuratus
XP_001177830
296
34057
L272
K
R
W
N
R
A
K
L
T
L
L
Q
R
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P49227
301
34418
T272
R
Y
N
L
K
K
L
T
Y
E
E
R
K
N
K
Baker's Yeast
Sacchar. cerevisiae
P26321
297
33724
S269
K
E
Q
Y
A
A
E
S
K
K
Y
R
Q
T
K
Red Bread Mold
Neurospora crassa
O59953
301
34393
S274
K
E
E
W
K
A
E
S
L
K
Y
K
K
S
K
Conservation
Percent
Protein Identity:
100
73.1
76
82.8
N.A.
98.3
98.6
N.A.
81.5
95.2
91.5
84.8
N.A.
67.2
N.A.
58.2
73
Protein Similarity:
100
73.1
76.4
83.1
N.A.
99.3
99.6
N.A.
82.6
98.6
95.9
94.9
N.A.
82.6
N.A.
75.4
84.8
P-Site Identity:
100
100
0
6.6
N.A.
100
100
N.A.
100
80
80
73.3
N.A.
40
N.A.
6.6
0
P-Site Similarity:
100
100
13.3
13.3
N.A.
100
100
N.A.
100
80
86.6
93.3
N.A.
66.6
N.A.
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.1
48.8
51.5
Protein Similarity:
N.A.
N.A.
N.A.
71.4
67
71.7
P-Site Identity:
N.A.
N.A.
N.A.
26.6
6.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
33.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
25
19
7
0
7
44
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
7
0
0
7
0
7
50
7
% D
% Glu:
0
13
7
0
0
0
13
0
0
19
7
7
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
25
0
0
0
25
69
7
0
7
13
7
57
69
13
25
% K
% Leu:
0
0
0
7
0
0
25
19
57
7
7
0
7
0
0
% L
% Met:
0
7
0
0
0
7
38
0
0
7
0
0
0
7
0
% M
% Asn:
0
7
63
7
7
0
0
0
7
0
0
0
0
7
0
% N
% Pro:
0
0
0
7
32
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
7
0
0
0
0
0
7
57
7
7
0
7
% Q
% Arg:
63
13
7
44
7
0
7
0
0
0
7
25
13
7
50
% R
% Ser:
0
0
0
7
0
0
7
57
0
0
0
0
0
7
0
% S
% Thr:
0
0
0
7
7
0
0
19
13
0
0
0
0
13
0
% T
% Val:
0
7
0
0
0
7
0
0
0
0
0
0
0
0
7
% V
% Trp:
7
50
7
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
7
0
0
0
0
13
7
13
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _